Comparison of Burrows-Wheeler Transform-Based Mapping Algorithms Used in High-Throughput Whole-Genome Sequencing: Application to Illumina Data for Livestock Genomes.

Comparison of Burrows-Wheeler Transform-Based Mapping Algorithms Used in High-Throughput Whole-Genome Sequencing: Application to Illumina Data for Livestock Genomes.

Ongoing developments and price decreases in next-generation sequencing (NGS) applied sciences have led to a rise of their software, which has drastically enhanced the fields of genetics and genomics. Mapping sequence reads onto a reference genome is a elementary step within the evaluation of NGS information. Environment friendly alignment of the reads onto the reference genome with […]

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Hardware acceleration of BWA-MEM genomic short read mapping for longer read lengths.

Hardware acceleration of BWA-MEM genomic short read mapping for longer read lengths.

We current our work on {hardware} accelerated genomics pipelines, utilizing both FPGAs or GPUs to speed up execution of BWA-MEM, a widely-used algorithm for genomic brief learn mapping. The mapping stage can take as much as 40% of total processing time for genomics pipelines. Our implementation offloads the Seed Extension perform, one of many predominant BWA-MEM computational features, onto an […]

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