The temperate bamboos (tribe Arundinarieae, Poaceae) are strongly supported as monophyly in latest molecular research, however taxonomic delineation and phylogenetic relationships inside the tribe lack decision. Right here, we sampled 39 species (36 temperate bamboos and three outgroups) for restriction-site related DNA sequencing (RAD-seq) with an emphasis on Phyllostachys clade and associated clades. Utilizing the […]
Continue ReadingCategory: Recombinant Proteins
Hobbes: optimized gram-based methods for efficient read alignment.
Latest advances in sequencing know-how have enabled the fast technology of billions of bases at comparatively low value. A vital first step in lots of sequencing functions is to map these reads to a reference genome. Nonetheless, when the reference genome is massive, discovering correct mappings poses a major computational problem because of the sheer quantity of […]
Continue ReadingHardware acceleration of BWA-MEM genomic short read mapping for longer read lengths.
We current our work on {hardware} accelerated genomics pipelines, utilizing both FPGAs or GPUs to speed up execution of BWA-MEM, a widely-used algorithm for genomic brief learn mapping. The mapping stage can take as much as 40% of total processing time for genomics pipelines. Our implementation offloads the Seed Extension perform, one of many predominant BWA-MEM computational features, onto an […]
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